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- Ph.D.: Electrical and Computer Engineering,
Purdue, 1995
- M.S.: Electrical and Computer Engineering,
Purdue, 1990
- B.S.: Electrical
and Computer
Engineering, Michigan Tech., 1988
I am a Professor in the
Department of Computer Science and Engineering
at the University of South Carolina.
I also serve as the director for the Bioinformatics core of the INBRE Project. My principal research interests are the implementation of mathematical,
statistical and engineering techniques in the area of computational biology, bioinformatics, and
medical informatics. A more
specific area of my actively funded research is the problem of protein folding,
protein/ligand and protein/protein interaction.
-
Computational Biology
-
Bioinformatics and Medical informatics
- Computational Medicine
-
Artificial Intelligence
-
Optimization
-
Parallel algorithms and architectures
- CSCE
240: Introduction to Software Engineering (Fall 2010, Spring 2011)
- CSCE 769: Computational Structural Biology (Spring
2009, 2010)
- CSCE
245: Object-Oriented
Programming Techniques (Spring
05, 06, 07, 08, 09)
- BMEN
321: Biomedical Circuits Analysis
(Fall
2009)
- CSCE
206: Scientific Applications Programming (Fall
2008)
- CSCE
790R: Structural /
Protein
Bioinformatic (Fall
2005, 2006, 2007)
- CSCE
590F: Topics in Bioinformatics and Medical informatics (Fall
2004)
-
Shealy
P, Simin M, Park SH, Opella SJ, Valafar
H,
Simultaneous structure and dynamics of a membrane protein using
REDCRAFT: Membrane-bound form of Pf1 coat protein, J
Magn Reson.
2010 Nov;207(1):8-16. Epub 2010 Jul 30, PMID: 20829084
- Park
SH, Son WS, Mukhopadhyay R, Valafar
H,
Opella SJ., Phage-Induced Alignment of Membrane Proteins Enables the
Measurement and Structural Analysis of Residual Dipolar Couplings
with Dipolar Waves and lambda-Maps, J
Am Chem Soc.
2009 Oct 14;131(40):14140-1
- Mukhopadhyay
R, Miao X, Shealy
P, Valafar
H, Efficient
and accurate estimation of relative order tensors from λ-maps,
J
Magn Reson.
2009 Jun;198(2):236-47. Epub 2009 Mar 5. PMID: 19345125
- Bryson
M, Tian F, Prestegard JH, Valafar
H,
REDCRAFT: A tool for simultaneous characterization of protein
backbone structure and motion from RDC data. J
Magn Reson.
2008 Apr;191(2):322-34, PMC2728087
- Miao
X, Mukhopadhyay R, Valafar
H,
Estimation of relative order tensors, and reconstruction of vectors
in space using unassigned RDC data and its application, J
Magn Reson.
2008 Oct;194(2):202-11, PMC2669903
- Miao
X, Waddell PJ, Valafar
H,
TALI: local alignment of protein structures using backbone torsion
angles, J Bioinform Comput Biol. 2008 Feb;6(1):163-81.
- Prestegard
JH, Mayer KL, Valafar
H,
Benison GC., Determination of protein backbone structures from
residual dipolar couplings, Methods Enzymol. 2005;394:175-209,
PMC1808351
- Valafar
H,
Mayer KL, Bougault CM, LeBlond PD, Jenney FE Jr, Brereton PS, Adams
MW, Prestegard JH, Backbone
solution structures of proteins using residual dipolar couplings:
application to a novel structural genomics target, J Struct Funct
Genomics. 2004;5(4):241-54, PMC1815388
- H.
Valafar,
Prestegard J.H., REDCAT: A Residual Dipolar Coupling Analysis Tool.
Journal
of Magnetic Resonance
167 (2004) 228-241
- Fang
T, Valafar
H.,
and Prestegard J., A
Dipolar Coupling Based Strategy for Simultaneous Resonance
Assignment and Structure Determination of Protein Backbones,
Journal
of the American Chemical Society;
2001
-
Al-Hashimi
HM, Valafar
H,
et al., Variation of molecular alignment as a means of resolving
orientational ambiguities in protein structures from dipolar
couplings. J
MAGN RESON
143: (2) 402-406 APR 2000.
Complete
list of publications
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